This unique book presents extensive analysis and discussion from the Pan-Asia ICT R&D Grants Programme covering 56 projects in 18 countries across Asia-Pacific. In addition to inputs from the ICT4D project heads, the book features insights from 6 ICT experts who personally visited these projects for assessments, as well as the key take-aways from a 3-day Learning Forum bringing all project heads and assessment experts together with donors and sponsors of this ambitious ICT4D initiative. What have been the key contributions of ICTs to development projects in healthcare, education, gender equity, agriculture, environment, disaster management and policy research? How can such ICT4D projects reach sustainability, replicability and scalability? What are the challenges involved in capacity building and execution for such social entrepreneurship projects? And what new horizons open up for these regional initiatives in the future? These are the key questions addressed in this publication.